The expression of TLR2 in BMMC was confirmed to be higher in ZAP-70+ (defined as cytoplasmatic expression >20% CLL cells) patients compared to ZAP-70−, with a median 0.2225 vs. 0.1885 (p = 0.0014), respectively (Figure 3B). Here, TLR2 is linked to B-cell chronic lymphocytic leukemia.