The expression of TLR7 and TLR9 was significantly higher in CLL patients compared to HVs (0.4790 vs. 0.1877, p < 0.0001), (0.3735 vs. 0.1066, p < 0.0001), respectively (Figure 1B,C). The gene discussed is TLR7; the disease is B-cell chronic lymphocytic leukemia.