Moreover, Pedram et al. [51] (Azerbaijan population) and Hashemi et al. [5] (Southeast Iranian population) found that MDM4 rs4245739 had no significant association with breast cancer clinicopathological factors, such as age, involved breast side, tumor size and type, grade of tumor, count of involved lymph nodes and stage of cancer, status of receptors. This evidence concerns the gene MDM4 and breast carcinoma.