INS and metabolic syndrome: Therefore, it can be assumed that, on the contrary, the transplantation of a healthy microbiome in a subject affected by metabolic syndrome determines an improvement in clinical parameters, as was demonstrated by Vrieze et al.: after six weeks from transplantation of gut microbiome of healthy people into patients with metabolic syndrome, an increase in insulin sensitivity and a decrease of body mass index (BMI) of the recipients was observed [40].