CUBN and Miyoshi myopathy: Recent studies of the antigens targeted by monoclonal Igs based on novel infectious antigen microarrays and immunoassays, indicated that chronic stimulation by an infectious pathogen or by a self-antigen, notably glucosylsphingosine (GlcSph), was a frequent pathogenic mechanism in MGUS and in MM [4,5,6,7,8,9,10].