F508del accounted for 30.4% of alleles, while 17 other CF-causing variants accounted for the 27.4% (28/102 alleles), and six different VCC variants for the 26.5% (27 alleles); finally, for the 12.7% (13 alleles), it was reported that variants had not known clinical consequences (alterations not present in CFTR mutation database and/or in CFTR2 database or not identified). This evidence concerns the gene CFTR and cystic fibrosis.