CCR3 and Increased total eosinophil count: In clinical studies with asthmatics, it was shown that treatment with an anti-sense TPI ASM8 (4 mg bid and 8 mg o.d. inhaled for 4 days) directed against the β common chain and CCR3, attenuated Ag-induced airway eosinophilia [66,74] as well as CCR3+HPC and EoP numbers [67].