It has been confirmed that RANTES is released by human subcutaneous adipose tissue in vivo, and RANTES concentrations in slim subjects (median 14.5 ng/mL) are lower than in obese subjects (median 29.4 ng/mL) and subjects with morbid obesity (median 57.0 ng/mL), but their share in the total concentration of circulating RANTES produced by various types of adipose tissue deposits is not decisive. The gene discussed is CCL5; the disease is morbid obesity.