CLEC12A and acute myeloid leukemia: C-type lectin domain family 12 member A (CLEC12A; UniProtKB-Q5QGZ9), also known as c-type lectin-like molecule-1 (CLL-1), is an ITIM-containing inhibitory transmembrane glycoprotein expressed on more than 80% of AML blasts as well as leukemic stem cells.