COMMD1 and AIDS dementia complex: Further bioinformatic analysis demonstrated that COMMD1 expression is significantly upregulated in both the ADC and SCC subtypes of NSCLC, with the relative expression elevated in ADC (n = 515, p = 0.0035) and SCC (n = 503, p = 0.0013), compared to non-malignant tissue (Figure 2C).