COMMD1 and lung cancer: As COMMD1 is overexpressed in NSCLC lung cancer cell lines, we employed two different siRNA sequences (#1 and #2) that target the COMMD1 transcript, as well as a negative control siRNA to deplete COMMD1 from HBEC3-KT, H460, H1975 and CRL5889 cell lines, as they represent the bronchial epithelial, LCC, ADC and SCC subtypes respectively (Figure 4A).