CDH1 and neoplasm: In addition, it has also been shown that MMPs display other biological activities related to tumor progression, such as the induction of proliferation [38,39], apoptosis-resistant cells [40], neoangiogenesis [41], and the facilitation of EMT by increasing cell mobility [42,43] or by repressing the expression of E-cadherin and other cell surface adhesion molecules [44,45].