CD8A and alopecia areata: Additionally, in alopecia areata (AA), a disease caused by attack of the bulb region of the hair follicle by autoreactive CD8+ T cells, higher numbers of peribulbar CD103+ CD8+ T cells and increased CD69+ and CD103+ T cell numbers were found to be present in lesional skin from AA patients compared to non-lesional skin and healthy controls [45,46,50].