It was demonstrated that exosomes derived from tumours contained antigen-presenting molecules (MHC class-I heat-shock proteins), tetraspanins (CD81) and other tumour antigens (Her2/Neu, Mart1, TRP and gp100) [100], which are very important for stimulation of immune cells against tumours with growth inhibition. The gene discussed is ERBB2; the disease is neoplasm.