Moreover, sequencing analyses, including analyses of previously known SUA-associating loci, found no disease-associated non-synonymous mutations in GLUT9 and URAT1. Although two mutations, c.73G>A (p.G25R, rs2276961) and c.844G>A (p.V282I, rs16890979), were found in GLUT9; however, previous studies have shown that they would not cause hyperuricemia/gout [30,31]. The gene discussed is SLC2A9; the disease is gout.