Other molecular abnormalities, such as increased expression of c-KIT, amplification of MYC family members (MYC, MYC lung carcinoma-derived homolog 1 [MYCL1], MYC neuroblastoma-derived homolog [MYCN]), and loss of PTEN have also been described in subsets of SCLC [54,55,56,57,58]. The gene discussed is KIT; the disease is small cell lung carcinoma.