There were also some specific modules detected exclusively by different methods, such as HBB/MMP9/PTX3/TIMP3 in GN, and CDH3/CDH5/CDH13 and IGFBP3/WFS1/CHRD-L1/CP/CYR61/GOLM1/SPARCL1 in LPA. The gene discussed is TIMP3; the disease is ganglioneuroma.