Considering that a lack of significant differences in IL-1β concentration between groups of endometriosis and non-endometriosis (but with other gynecological diseases) was observed in this study, similarly to other studies, it may be concluded that a group of healthy women, without any diagnosed or treated diseases, should be used as a control group for the comparison of cytokine expression in endometriosis. The gene discussed is IL1B; the disease is female reproductive system disorder.