CD8A and neoplasm: The increase of tumor-infiltrating and IFNγ-secreting CD4+ and CD8+ T cells, and the elevation of key Th-1 and CTL (cytotoxic T lymphocyte)-driving cytokines IFNγ and IL-12, together reveals that IP-001 favors the initiation of cytotoxic T lymphocytes with T-helper type 1 response.