Interferon-gamma (IFN-γ) and interleukin-2 (IL-2) expression in tumor tissue was much higher in mice treated with oxaliplatin with or without B. breve strains (B. bre JCM92 and B. bre Bb03) compared to IFN-γ and IL-2 expression in vehicle-treated mice. This evidence concerns the gene IL2 and neoplasm.