Having established the negative correlation of tumor immune infiltration with CDK2/4/6 expression in GBM and melanoma, we wonder if there will be an association between these genes alterations and immune infiltration, to this ends we queried the correlation between different somatic copy number alterations of CDK2/4/6/STAT3 and immune cell infiltration in glioblastoma and melanoma. This evidence concerns the gene STAT3 and melanoma.