No statistically significant differences were observed between bortezomib-sensitive and bortezomib-refractory MM patients with regard to bone involvement at diagnosis (p = 0.96), calcium > 2.75 mmol/L at diagnosis (p = 0.89), creatinine > 2 mg/dL at diagnosis (p = 0.31) or Hb < 10 g/dL at diagnosis (p = 0.73) and ISS (p = 0.86). This evidence concerns the gene GSTM1 and Miyoshi myopathy.