LEP and Large for gestational age: Thus, Zheng J. et al. reported that placental microbiota significantly differs between normal-weight and macrosomic newborns, with higher abundance of Acinetobacter, Bifidobacterium, Mycobacterium, Prevotellaceae, Dyella, Bacteroidales, and Romboutsia in macrosomia, correlated with an elevation of IGF-1 and insulin and, conversely, with a reduction in leptin levels [68].