HNRNPA1 and chronic myelogenous leukemia, BCR-ABL1 positive: Gao et al. found that in CML, tumor-suppressive microRNAs, especially the miR-320 secreted by leukemic cells, is taken up by adjacent BM-MSCs via heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) and significantly inhibit osteogenesis, remaking it into a bone marrow niche favorable for CML progression [91].