This small molecule blocks the binding of BH3 proteins (mostly Bim) to Bcl-2, allowing the activation of BCL2 Antagonist/Killer/BCL2 associated X (Bak/Bax) on the surface of mitochondria leading to cell death of cancer cells because of the release of cytochrome C through a mitochondrial outer membrane permeabilization (MOMP) process. Here, BCL2 is linked to cancer.