PER3 and cancer: The top intracellular pathways of the 12 overlapping genes were associated with circadian rhythms and entrainment (Arntl, Cry2, Per2, Per3, Bhlhe41), the cell cycle (Cdkn1a, Wee1), the oxytocin signaling pathway (Cdkn1a, Rcan1), and transcriptional misregulation in cancer (Cdkn1a, Per2) (Table 5).