These include Spon2, Adam19, Arntl, Cdkn1a, Cry2, Per2, Per3, Wee1, Rcan1, Slc41a3, Errfi1, and Bhlhe41, which are related to numerous cardiovascular and degenerative diseases of other organs as well as varying aging processes. This evidence concerns the gene ERRFI1 and neurodegenerative disease.