While we found a main effect of genotype with a small significant increase in total distance traveled by P2Y12−/− mice (Figure 3B; two-way ANOVA, F (1, 36) = 4.324, p = 0.0448), there was no significant difference in the center area exploration time (Figure 3C), suggesting a mild increase in locomotor activity with no difference in anxiety-like behavior as assayed by this simple test. The gene discussed is P2RY12; the disease is Anxiety.