Furthermore, according to the studies of Broncel et al., Hellström et al. and Sikora et al., chokeberry polyphenols are capable of inhibiting the angiotensin I-converting enzyme (ACE) activity both in vitro and in vivo, and lowering the blood pressure of both spontaneously hypertensive rats and patients with MS [103,119,124]. Here, ACE is linked to myeloid sarcoma.