In addition, there were a number of common predicted target genes with a role in cell migration and cell-to-cell junction assembly (NTNG2, NEO1, JAM2, F11R, PARDG6, PTPRF, NFASC, SDC3, PLEKHG5, HIC1), as well as genes with semaphoring and ephrin receptor activity (PLXNP1, SE-MA6C, SEMA4C, SRGAP1), which are known to play a role in immune pathologies and neurodegenerative diseases [79]. Here, JAM2 is linked to neurodegenerative disease.