Crawford and colleagues screened 122 gliomas, 22 non-glial tumors, and 32 non-tumor autopsy controls derived from pediatric subjects for the presence of HHV-6 by in situ hybridization, nested PCR, and immunohistochemistry, and revealed higher rates of expression of the viral proteins U57 (major capsid protein) and U31 (large tegument protein) in tumors compared to non-tumor controls [66]. Here, SNORD57 is linked to neoplasm.