Analysis of the REpository for Molecular BRAin Neoplasia DaTa (REMBRANT) dataset [37] revealed that endogenous ERK5 mRNA expression is significantly increased in all grades of brain tumours compared with normal brain tissue (Figure 4A), and that increased ERK5 mRNA expression is associated with worse patient survival rates (Figure 4B). This evidence concerns the gene MAPK7 and brain neoplasm.