There are four human homologs (VPS13A–D) [35], and mutations in these genes result in chorea-acanthocytosis (ChAc) (VPS13A) [36,37,38], Cohen’s syndrome (VPS13B) [39], early-onset parkinsonism (VPS13C) [40] and childhood-onset movement disorder (VPS13D) [41,42]. The gene discussed is VPS13C; the disease is chorea-acanthocytosis.