There are four human homologs (VPS13A–D) [35], and mutations in these genes result in chorea-acanthocytosis (ChAc) (VPS13A) [36,37,38], Cohen’s syndrome (VPS13B) [39], early-onset parkinsonism (VPS13C) [40] and childhood-onset movement disorder (VPS13D) [41,42]. This evidence concerns the gene VPS13B and chorea-acanthocytosis.