Numerous protein kinases including AKT1, MAPK1/ERK, RPS6KA1/RSK1, cAMP-activated protein kinase (PKA), PAK1, PRKCI/nPKC-iota, PRKCE/nPKC-epsilon and PIM1 were reported to phosphorylate BAD in prostate cancer cells [135,136,137]. This evidence concerns the gene MAPK1 and Familial prostate cancer.