Analysis of gene expression repositories and published data identified BCL2, BCL2L1/BCLX, MCL1, BAX, BAK, BAD, BCL2L11/BIM, BBC3/PUMA, PMAIP1/NOXA, BIK and BID as members of the BCL-2 family proteins expressed in a normal prostate and in PCa. The gene discussed is BBC3; the disease is posterior cortical atrophy.