BCL2 and ovarian cancer: Interestingly, this group did not see an induction of the pro-survival proteins BIRC2, BIRC3, nor Bcl-2 when COL11A1 was overexpressed in A2780 and ES2 ovarian cancer cell lines, nor a reduction of these proteins when COL11A1 expression was knocked down in A2780CP70 ovarian cancer cell line.