In stark contrast, it has been shown in hematological malignancies including Acute Myeloid Leukemia (AML), Chronic Lymphocytic Leukemia (CLL), B-Cell Acute Lymphoblastic Leukemia (B-ALL), and Diffuse Large B-cell Lymphoma (DLBCL) that COL11A1 overexpression is associated with better prognosis [14]. The gene discussed is COL11A1; the disease is acute myeloid leukemia.