Similar associations have been reported in patients with established schizophrenia for TNF-α and IL-6 (Goldsmith et al., 2018b), in patients with first episode psychosis for IFN-γ (Mondelli et al., 2015) and more recently in individuals at ultra-high risk of psychosis with TNF-α and IL-6 (Goldsmith et al., 2018a). This evidence concerns the gene TNF and schizophrenia.