This article contains supplemental datasets of the recently published related research article <i>"Synthesis, Inverse Docking-Assisted Identification and in vitro Biological Characterization of Flavonol-based Analogs of Fisetin as c-Kit, CDK2 and mTOR Inhibitors against Melanoma and Non-melanoma Skin Cancers"</i> by Roy et al., [1]. This evidence concerns the gene CDK2 and skin cancer.