Figures 1C,D show the risk-score distribution and the survival status of individual in the high- and low-risk cluster. The variables including Age, Alb, PLT, PaO2/FiO2, LDH, HRCT, and etiology were incorporated into the nomogram (Figure 2). To facilitate the clinical application of our findings, we developed a web-based calculator (https://huangl.shinyapps.io/ARDSprognosis/) to predict prognosis of ARDS patients according to the nomogram (Figures 3A,B). This evidence concerns the gene ALB and acute respiratory distress syndrome.