The most significantly enriched lncRNA-hallmark pair is between CTD-3247F14.2 and “TNFA signaling via NFKB.” The observation showed that CTD-3247F14.2 was prone to correlate with genes involved in “TNFA signaling via NFKB” than those in other hallmarks, indicated potential regulatory roles of CTD-3247F14.2 for “TNFA signaling via NFKB” in prostate cancer. The gene discussed is TNF; the disease is prostate cancer.