CATSPER2 and deafness-infertility syndrome: Humans homozygous for a deletion in Chromosome 15 spanning STRC and CATSPER2 genes have been associated with Deafness-infertility syndrome (DIS), which presents itself as an early-onset deafness in males and females with modest symmetric sensorineural hearing loss (Dgany et al., 2002, p. 1); men present normal ejaculate volume, though sperm count, motility, and morphology are affected, which results in asthenoteratozoospermia and male infertility (Dgany et al., 2002, p. 1).