In the combined children with obesity and children with normal weight group, serum ALT positively correlated with levels of IL-6 (p = 0.0040), CRP (p = 0.0003), sICAM-1 (p = 0.0018), and leptin (p < 0.0001), but not with adiponectin (p = 0.5397) while BChE levels positively correlated with IL-6 (p = 0.0481), sICAM-1 (P partial = 0.0004), and leptin (p = 0.0047) levels, and negatively correlated with adiponectin (p = 0.0082). The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.