Reduces the expression of β-catenin protein level, which subsequently results in downregulation of its target protein cyclinD1 in both OAC and OSCCSelectively kills ABCG+ CSCs and inhibits tumor sphere formation in both OAC and OSCCReduces tumor volume and tumor weight alone or in combination with 5-flurouracil in both OAC and OSCC. Here, CCND1 is linked to neoplasm.