CACNA1H and diabetes mellitus: As CaV3.2 channel up-regulation is a common feature in the development and maintenance of multiple pain processes [48], and alterations of CaV3.2 channels glycosylation have been associated with the development of pain related to diabetes [43,45,49], understanding CaV3.2 trafficking and the impact of its glycosylation are of significant therapeutic relevance [50].