SLC6A1 and stroke disorder: To further confirm whether GAT-1 is a key mediator for EE-dependent functional recovery, AAV-CAG-EGFP-Cre was microinjected into the motor cortex of GAT-1flox/floxmice 3 days before stroke to specifically delete peri-infarct GAT-1, and motor function was measured 7 days before and 4, 12, 19, 26, and 33 days after stroke (Figure 6B).