Most of the remaining loci instead belonged to the other two pathways and have been implicated in the modulation of pathological traits associated to insulin resistance and T2D, as is the case of several genes encoding for mitogen‐activated proteins kinases (MAPK) and phospholipases (PLCB), or in the response to dietary stimuli, such as the insulin‐like growth factor 1 receptor (IGF1R) and FOXO genes (Figure 3, Table S3). Here, IGF1R is linked to type 2 diabetes mellitus.