More and more studies have shown that YWHAZ is upregulated in breast cancer, ovarian cancer, G2 endometrial adenocarcinoma, prostate cancer, and other types of genitourinary tumors and that it participates in cell growth, cell cycle, apoptosis, migration, and invasion (Jeda et al., 2014; Wang et al., 2017; Yang et al., 2019; Yu et al., 2020). This evidence concerns the gene YWHAZ and Familial prostate cancer.