When co-cultured with chronic myeloid leukemia (CML) cell lysates, the expression of co-stimulatory molecules (CD40, CD80 and CD86) and antigen-presenting molecule HLA-DR on Vγ9Vδ2 T cells could be strongly up-regulated. The gene discussed is CD80; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.