The levels of ER stress proteins in the stroke group were increased, including GRP78 (1.3, 1 day; 1.5, 3 days, Figure 3A), IRE1α (1.0, 1 and 3 days, Figure 3B), PERK (0.4, 1 day; 0.8, 3 days, Figure 3C), ATF6 (0.6, 1 day; 0.7, 3 days, Figure 3D), CHOP (0.7, 1 day; 0.9, 3 days, Figure 3E) and Caspase-12 (1.5, 1 day; 1.1, 3 days, Figure 3F). This evidence concerns the gene CASP12 and stroke disorder.