GFPT1 and Insulin resistance: Because of its role in the development of insulin resistance in type 2 diabetes39, studies on GFAT are mostly focused on mammals, whereas there have been rather few studies on the GFAT gene in insects for a long time and it has only been reported in Drosophila melanogaster, Aedes aegypti, Haemaphysalis longicornis at present21,40,41.