No correlation was found between serum SCFA levels and Th1 or Th17 cell frequencies (%CD4+ T-cells) (n = 25 CIS/MS) or expression of IL-10, IFNγ or IL-17 in total CD4+ T-cells (n = 11 CIS/MS) (data not shown). This evidence concerns the gene IFNG and in situ carcinoma.