MYC and neoplasm: Recent studies had shown that MYC overexpression waspositively correlated with glioma grade and that increased MYC level was observed inapproximately 60-80% gliomas.35 Inhibition of MYC repressed theproliferation of tumor cells, damages cell activity, and promotedapoptosis.36 Indeed, our data showed that MYC knockdown inU251 cells visibly decreased anti-apoptosis, cell viability, and cell invasion.