Inaddition, according to the data analysis of online tools (GEPIA2 and CGGAdatabases), we found that MYC expression was positively correlated with PNO1(Supplementary Fig. S2E–G).All of above results suggest that MYC overexpression may help drive glioma bytriggering PNO1 overexpression. This evidence concerns the gene PNO1 and glioma.