CHI3L1 and autoimmune hepatitis: To evaluate whether CHI3L1 mediates the immunosuppressive effects of hUC-MSCs in vivo, experimental AIH, a commonly used experimental model to study immune-mediated liver injury19, was induced by Con A (15 mg/kg) in mice, and PBS, MSCshNTC or MSCshCHI3L1 was administered intravenously.