Compared to the GBM-exo group, the GBM-exo + sh-LINC00470 group had decreased LINC00470 expression (Fig. 4a, P < 0.05), increased acidic autophagosomes (Fig. 4b), upregulated expression levels of LC3-II/LC3-I and Beclin1, declined expression of p62 (Fig. 4c, P < 0.05), downregulated proliferation ability (Fig. 4d–e, P < 0.05) and increased number of G1-phase cells (Fig. 4f, P < 0.05). This evidence concerns the gene LINC00470 and glioblastoma.